Universitetet i Oslo

Oslo

Maren Retterstøl Olaisen

Rådgiver (for spørsmål om elektronisk søknad)

Knut Lundin

Professor

<h2>About the position</h2>A two-year 50% position as Scientist (SKO 1109) with background in clinical nutrition and/or gastroenterology is available at the Norwegian Coeliac Disease Research Centre, Institute of clinical medicine, University of Oslo.  The position is part of a multi-PI project split between the research groups of Professor Ludvig M. Sollid at the Department of Immunology, Institute of Clinical Medicine, Faculty of Medicine, Professor Knut Lundin at Department of transplantation medicine, Institute of Clinical Medicine, University of Oslo and Dr. Jorunn Stamnæs at the Proteomics Core Facility at Oslo University Hospital and University of Oslo. <h2>More about the position </h2>The position is funded by Coeliac UK as part of a research project that will explore whether low-level gluten exposure (i.e. levels below the current definition of gluten free diet) can cause gut inflammation and gut damage in subjects with coeliac disease. Specifically, we will in a placebo-controlled oral gluten challenge trial seek to determine whether repeat low-dose of gluten can induce immune activation and low-level gut inflammation. The project builds upon recent data from the Centre (Stamnæs et al J Clin Invest 2025 PMID 40828615) that identifies a central role for interferon gamma in the induction of gut damage and remodeling. In this project we will perform multiparameter flow-cytometry of gut biopsies collected from patients subjected to low-dose gluten challenge as well as short-term ex vivo biopsy cultures to determine the source of inflammatory cytokines and experimentally establish a mechanistic link between immune cell activation, cytokine secretion and gut inflammation and remodeling in response to dietary gluten. This project will rely on advanced cell biology methods including establishment ex vivo short-term intestinal biopsy culture followed by down-stream processing and analysis by methods such as flow cytometry, microscopy imaging and mass spectrometry-based proteomics. The successful applicant will join a world leading research environment on celiac disease with a strong track record in mucosal immunology, cell biology and tissue processing. The specific tasks for the scientist will focus on recruitment of patients, screning for eligibility and clinical microchallenge with gluten. The candidate will work in a multidisciplinary team with access to relevant training and support. The workplace will be in the research group of prof. Knut Lundin at the Department of transplantation medicine at Oslo University Hospital – Rikshospitalet. Office facilities will be offered at Department of nutrition, University of Oslo. The duration of appointment is 2 years. <h2>Qualification requirements</h2><ul><li>The applicants must hold PhD in clinical nutrition, biology, immunology or a related field</li><li>Experience with gluten challenge studies of coeliac disease patients is a requirement</li><li>Experience and knowledge on human mucosal immunology is strong advantage</li><li>Fluent oral and written communication skills in English.</li><li>Good written and oral proficiency in Norwegian (or another Scandinavian language). If the employee cannot document skills in</li><li>Norwegian, Swedish, or Danish at level A2 upon employment, UiO will offer Norwegian language training. The employee must complete training equivalent to at least 15 credits by the end of the employment period.</li></ul> <h2>We need different perspectives in our work </h2>UiO is an open and internationally oriented comprehensive university that strives to be an inclusive and diverse workplace and academic environment. You can read more about UiO’s work on equality, inclusion, and diversity at <a href="https://www.uio.no/english/about/strategy/gender-equality/index.html" rel="nofollow">uio.no</a>.We fulfill our mission most effectively when we draw upon our variety of experiences, backgrounds, and perspectives. We are looking for great colleagues—could you be the next one?We will provide appropriate accommodations should you need them. Relevant adjustments may include modifications to working hours, task adaptations, digital, technical, or physical adjustments, or other practical measures. If you have an immigrant background, a disability, or CV gaps, we encourage you to indicate this in the job application portal. We always invite at least one qualified candidate from each group for an interview. In this context, disability is defined as an applicant who identifies as having a disability that requires workplace or employment-related accommodations. For more details about the requirements, please refer to the <a href="https://arbeidsgiver.dfo.no/strategisk-hr/inkluderingsarbeid/bli-bedre-pa-rekruttering/hvordan-skrive-stillingsannonser-som-inkluderer/positiv-saerbehandling-nar-man-soker-jobb-i-staten" rel="nofollow">Employer portal</a> (Norwegian).The selections made in the job application portal are used for anonymized statistics that all state employers include in their annual reports. More information about gender equality initiatives at UiO can be found <a href="https://www.uio.no/english/for-employees/competence/gender-equality/index.html" rel="nofollow">here.</a>We hope you will apply for the position with us.  <h2>We offer </h2><ul><li>An exciting research environment with opportunities for academic development.</li><li>Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities.</li><li>Membership in the <a href="https://www.spk.no/en/" rel="nofollow">Statens Pensjonskasse</a>, which is one of Norway&#39;s best pension schemes with beneficial mortgages and good insurance schemes.</li><li>Good <a href="https://www.uio.no/english/for-employees/employment/welfare/index.html" rel="nofollow">welfare schemes.</a></li><li>Opportunity of up to 1.5 hours a week of <a href="https://www.uio.no/english/for-employees/employment/welfare/exercise/" rel="nofollow">exercise during working hours.</a></li><li>A workplace with good development and career opportunities. </li><li>Salary in position as Scientist, position code 1109 in salary range NOK 650 000 to 750 000 depending on competence and experience. From the salary, 2 percent is deducted in statutory contributions to the State Pension Fund</li></ul>Read more about the benefits of working in the public sector at <a href="http://arbeidsgiver.difi.no/lonn-goder-og-reise" rel="nofollow">Employer Portal</a>. <h2>Application</h2>Your application should include:<ul><li>Application letter</li><li>Letters of recommendation</li><li>CV</li><li>A complete list of publications</li><li>Transcripts and certificates</li><li>Letters of recommendation</li><li>Contact information for 2-3 references</li></ul>Your CV must be entered in Jobbnorge’s CV form and cannot be submitted only as an attachment. This requirement is intended to ensure correct documentation and record-keeping in accordance with the Public Administration Act, Section 15. Application with attachments must be submitted via our recruitment system Jobbnorge, click &#34;Apply for this job&#34;.When applying for the position, we ask you to retrieve your education results from <a href="https://www.vitnemalsportalen.no/english/" rel="nofollow">Vitnemålsportalen.no</a>. If your education results are not available through Vitnemålsportalen, we ask you to upload copies of your transcripts or grades. Please note that all documentation must be in English or a Scandinavian language. <h2>General information</h2>Please note that we are unable to add documentation after the application deadline. As the deadline applies equally to all applicants, this policy ensures equal treatment throughout the recruitment process. If you experience difficulties uploading documents in Jobbnorge, please contact their customer service: Phone: &#43;47 75 54 22 20 or Email: <a href="mailto:support&#64;grade.com" rel="nofollow">support&#64;grade.com</a>  The primary method of communication throughout the process will be e-mails and messages through the recruitment system Jobbnorge. When you receive a notification of a message in Jobbnorge, please log in to read it, as it may be important. The best qualified candidates will invited for interviews. Applicant lists can be published in accordance with <a href="https://lovdata.no/dokument/NLE/lov/2006-05-19-16" rel="nofollow">Norwegian Freedom of Information Act</a> § 25. When you apply for a position with us, your name will appear on the public applicant list. It is possible to request to be excluded from this list. You must justify why you want an exemption from publication and we will then decide whether we can grant your request. If we cannot, you will hear from us. Please refer to  <a href="https://lovdata.no/dokument/SF/forskrift/2024-06-28-1392/KAPITTEL_3#KAPITTEL_3" rel="nofollow">Regulations for the Act on universities and colleges chapter 3</a> (Norwegian) and <a href="https://www.uio.no/english/about/regulations/personnel/academic/rules-use-research-post.html" rel="nofollow">Rules for the use of research posts SKO 1108, 1109, 1110 and 1183 at UiO.</a>The University of Oslo has a <a href="https://www.uio.no/english/for-employees/employment/work-results/agreement-rights-to-work-results.html" rel="nofollow">transfer agreement</a> with all employees to secure the rights to all research results and related intellectual property.

Scientist in clinical nutrition/gastroenterology