Universitetet i Oslo

Oslo

Alexander Grande

HR Officer

Kjetil Taskén

Professor II

Johanna Olweus

<h2>About the position / About the job</h2><p>A position as Researcher (SKO1109) is open in the Experimental Cancer Immunotherapy Group led by Johanna Olweus, MD, PhD, at Deptartment of Cancer Immunology, Institute for Cancer Research, Division of Cancer Medicine, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital Radiumhospitalet, from April 2026 to February 2027.</p> <br /><h2>Project description</h2><p>The project involves validation of new T-cell receptor-based immunotherapies in vitro for safety and efficacy, and in advanced in vivo mouse models. A wide spectrum of methodologies will be used, including standard molecular biology techniques such as DNA/RNA isolation and plasmid preparation, retroviral transduction of T cells, culture of primary T cells, multiparameter (up to 12 colors) flow cytometry assays including functional T-cell assays (cytokine release, cytotoxicity, proliferation), culture of organoids, establishment of patient-derived xenograft models and evaluation of TCR-T cell therapy in such models.ion in more detail and/or present the project description.</p><p>Olweus is Head of the Dept. of Cancer Immunology at Oslo University Hospital Radiumhospitalet and leads a research group in the department and holds a position as Professor at the University of Oslo (UiO). The main focus of the research group of Olweus is to develop novel T-cell receptor-based cancer immunotherapies and new technologies for target and TCR identification, and to couple clinical immunotherapy trials with penetrating mechanistic analyses. The research is performed in an interdisciplinary and translational program. The enthusiastic research team of 20 people is highly international and conducts research in close collaboration with world-leading international collaborators at institutions such as Netherlands Cancer Institute and Karolinska Institutet.</p><br /><h2>Your main tasks will be</h2><p><strong>In Vitro work</strong></p><ul><li>Perform DNA/RNA isolation and plasmid preparation.</li><li>Engineer T cells using retroviral transduction.</li><li>Culture and maintain primary T cells and organoids.</li><li>Run multiparameter flow cytometry and functional T‑cell assays.</li></ul><p><strong>In vivo work</strong></p><ul><li>Establish and monitor patient-derived xenograft (PDX) mouse models.</li><li>Evaluate safety and efficacy of TCR-T cell therapies in mouse experiments.</li><li>Collect and process tissues for downstream analyses.</li></ul><p><strong>Data &amp; documentation</strong></p><ul><li>Analyze flow cytometry and functional assay data.</li><li>Document experiments and prepare figures and summaries</li></ul><p><strong>Collaboration &amp; development</strong></p><ul><li>Work in an interdisciplinary team and with international collaborators.</li><li>Contribute to development and optimization of TCR discovery and validation methods.</li></ul><br /><h2>Qualifications</h2><p><strong>Required qualifications</strong></p><ul><li>PhD in immunology and at least three years of postdoctoral experience in the field of experimental T cell immunology</li><li>Strong publication record in experimental immunology</li><li>Felasa C certificate to do animal experiments</li><li>Proficient in written and spoken English </li><li>Excellent team working and communications skills</li></ul> <br /><h2>Personal qualities</h2><p>We seek a candidate who is dedicated, resilient, and with genuine enthusiasm for experimentation and scientific discovery.</p><p>Employment in the position is based on a comprehensive assessment of all qualification requirements applicable to the position, including personal qualifications.</p><br /><h2>We need different perspectives in our work </h2><p>UiO is an open and internationally oriented comprehensive university that strives to be an inclusive and diverse workplace and academic environment. You can read more about UiO’s work on equality, inclusion, and diversity at <a href="https://www.uio.no/english/about/strategy/gender-equality/index.html" rel="nofollow">uio.no</a>.</p><p>We fulfill our mission most effectively when we draw upon our variety of experiences, backgrounds, and perspectives. We are looking for great colleagues—could you be the next one?</p><p>We will do our best to accommodate your needs. Relevant adjustments may include modifications to working hours, task adaptations, digital, technical, or physical adjustments, or other practical measures.</p> <p>If you have an immigrant background, a disability, or CV gaps, we encourage you to indicate this in the job application portal. We always invite at least one qualified candidate from each group for an interview. In this context, disability is defined as an applicant who identifies as having a disability that requires workplace or employment-related accommodations. For more details about the requirements, please refer to the <a href="https://arbeidsgiver.dfo.no/strategisk-hr/inkluderingsarbeid/bli-bedre-pa-rekruttering/hvordan-skrive-stillingsannonser-som-inkluderer/positiv-saerbehandling-nar-man-soker-jobb-i-staten" rel="nofollow">Employer portal</a> (Norwegian).</p><p>The selections made in the job application portal are used for anonymized statistics that all state employers include in their annual reports.<br /><br />More information about gender equality initiatives at UiO can be found <a href="https://www.uio.no/english/for-employees/competence/gender-equality/index.html" rel="nofollow">here.</a></p><p>We hope you will apply for the position with us. </p><br /><h2>We offer / We can offer you / Why should you choose us?</h2><ul><li>Exciting and meaningful tasks in an organization with an important societal mission, contributing to knowledge development, education, and enlightenment that promote sustainable, fair, and knowledge-based societal development.</li><li>A dynamic and stimulating scientific environment in a young, enthusiastic and motivated team of biologists and MDs</li><li>Good <a href="https://www.uio.no/english/for-employees/employment/welfare/index.html" rel="nofollow">welfare schemes.</a></li><li>Opportunity of up to 1.5 hours a week of <a href="https://www.uio.no/english/for-employees/employment/welfare/exercise/" rel="nofollow">exercise during working hours.</a></li><li>A workplace with good development and career opportunities. </li><li>Membership in the <a href="https://www.spk.no/en/" rel="nofollow">Statens Pensjonskasse</a>, which is one of Norway&#39;s best pension schemes with beneficial mortgages and good insurance schemes.</li><li>Salary in position as Researcher, position code 1108 /1109 in salary range NOK from 675 000,- to 775 000,- depending on competence and experience. From the salary, 2 percent is deducted in statutory contributions to the State Pension Fund.</li></ul><p>The Institute of Cancer Research is at the international forefront and houses top modern (2009) and excellent lab facilities with a wide range of core facilities (animal, light and electron microscopy, flow cytometry, genomics and bioinformatics, MR), with additional core facilities (mass spec etc) at the Rikshospitalet and UiO sites. We </p><p> </p><p>Read more about the benefits of working in the public sector at <a href="http://arbeidsgiver.difi.no/lonn-goder-og-reise" rel="nofollow">Employer Portal</a>.</p><br /><h2>Application</h2><p>Your application should include:</p><ul><li>Application letter.</li><li>CV.</li><li>A complete list of publications.</li><li>Transcripts and certificates.</li><li>Contact information for 2-3 references.</li></ul><p>Application with attachments must be submitted via our recruitment system Jobbnorge, click &#34;Apply for the position&#34;.</p><p>When applying for the position, we ask you to retrieve your education results from <a href="https://www.vitnemalsportalen.no/english/" rel="nofollow">Vitnemålsportalen.no</a>. If your education results are not available through Vitnemålsportalen, we ask you to upload copies of your transcripts or grades. Please note that all documentation must be in English or a Scandinavian language.</p><br /><h2>General information</h2><p>The best qualified candidates will invited for interviews.</p><p>Applicant lists can be published in accordance with <a href="https://lovdata.no/dokument/NLE/lov/2006-05-19-16" rel="nofollow">Norwegian Freedom of Information Act</a> § 25. When you apply for a position with us, your name will appear on the public applicant list. It is possible to request to be excluded from this list. You must justify why you want an exemption from publication and we will then decide whether we can grant your request. If we cannot, you will hear from us.</p> <p>Please refer to  <a href="https://www.uio.no/english/about/regulations/personnel/academic/rules-use-research-post.html" rel="nofollow">Rules for the use of research posts SKO 1108, 1109, 1110 and 1183 at UiO.</a></p><p>The University of Oslo has a <a href="https://www.uio.no/english/for-employees/employment/work-results/agreement-rights-to-work-results.html" rel="nofollow">transfer agreement</a> with all employees that is intended to secure the rights to all research results etc.</p><br />

Vikariat

Forsker SKO 1109 - KRE

Researcher in Cancer Immunotherapy