Oslo Universitetssykehus Hf

Oslo

A 3-year Researcher position (postdoctoral level) is available at the Department of Pediatric Research, Oslo University Hospital, Oslo, and the Department of Molecular Medicine, Institute of Basic Medical Sciences, UiO. The position is affiliated with the research groups of Dr Gareth Sullivan and Associate Professor Coen Campsteijn. The position is funded by the South-Eastern Norway Regional Health Authority (HSØ) and is available from September 01, 2025, for three years. Start date is negotiable. Oslo University Hospital and the University of Oslo are workplaces with a great diversity. We believe this to be a crucial advantage for solving biomedical challenges and tasks in the best possible way. We aim for this diversity to be reflected among the applicants for our positions, and we encourage all qualified candidates, regardless of background, to apply.Oslo University Hospital is a workplace with great diversity. We believe this is crucial to solving our tasks
in the best possible way. We want this diversity to be reflected among the
applicants for our positions, and encourage all qualified candidates,
regardless of background, to apply.&nbsp; &nbsp; 
<h4 class="navds-heading navds-heading--xsmall navds-typo--spacing">Job Description</h4>We seek a highly motivated Post-doctoral candidate to uncover the molecular mechanisms that drives a healthy liver to Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Metabolic Dysfunction-Associated Steatohepatitis (MASH), a phenomenon that poses a major societal biomedical challenge. Despite intense research we lack fundamental insight in the molecular processes that underlie the etiology of MASLD and its progression to highly pathological states like MASH and ultimately hepatocellular carcinoma (HCC). Recent advances have started to reveal how biomechanical forces and alteration in nuclear structure directly control cell function, identity and fate. In this project, we will explore biomechanics forces, nuclear stress and dysfunction as drives of MASLD and MASH. The project is an ongoing collaboration between the Sullivan and Campsteijn labs. The successful applicant will work in an interdisciplinary team together with an additional postdoctoral scientist hired on this project, and in collaboration with the groups of Associate Professor Frode Norheim and Professor Knut Tomas Dalen.The project focuses on developing advanced induced pluripotent stem cell (iPSCs) models of MASLD and explore their behaviour using a using a combination of genetics, transcriptomics, proteomics, and advanced light microscopy to dissect the mechanistic underpinnings of MASLD/MASH.&nbsp;<h4 class="navds-heading navds-heading--xsmall navds-typo--spacing">Qualifications and Requirements&nbsp;&nbsp;</h4>We are looking for a highly motivated, skilled, and independent researcher with extensive hands-on experience in basic human pluripotent stem cell research, organoid culture and liver development and disease. The candidate should have the following qualifications:<ul><li>PhD in cell biology, molecular biology, biochemistry, or equivalent </li><li>Strong experience in molecular and/cell biology techniques, including cell culture and genetics (CRISPR/Cas9) </li><li>Hands-on experience with human pluripotent stem cell culture </li><li>Proficiency in fixed and live cell fluorescence microscopy and image analysis </li><li>Track record of scientific productivity (e.g., publications in international journals)</li><li>Experience with figure preparation and manuscript writing </li><li>Fluent in English (oral and written)</li><li>Research integrity, motivation, and willingness to learn new methods</li><li>Excellent teamwork and communication skills</li></ul>How to apply:Submit your application through Webcruiter with the following documents: Application letter (1–2 pages) detailing your motivation and suitability for the position. Curriculum Vitae, including a list of publications and a summary of relevant skills. Contact information for two references from previous research environments. &nbsp; Incomplete applications (missing any of the above documents) or applications not submitted via Webcruiter will not be considered. Application deadline: July 10, 2025 Preferred start date: September, 2025 (negotiable)Contact information: Inquiries about the positions can be directed to group leader Dr. Gareth Sullivan <a rel="nofollow" href="mailto:garethsully@hotmail.com">garethsully@hotmail.com</a>&nbsp; <h4 class="navds-heading navds-heading--xsmall navds-typo--spacing">We offer</h4><ul><li>An exciting/innovative research project within a collaborative and supportive team</li><li>A stimulating environment with access to state-of-the-art imaging facilities </li><li>A healthy balance between independent research and close mentorship </li><li>Career development support and guidance </li><li>A full-time three-year employment (3 years) </li><li>Salary according to Oslo University Hospital guidelines </li><li>A flexible, family-friendly workplace that supports work–life balance </li></ul>Oslo University Hospital is a highly specialised hospital in charge of extensive regional and local hospital assignments. As Scandinavia’s largest hospital, we carry out more than 1.2 million patient treatments each year. The hospital has a nationwide responsibility for a number of national and multi-regional assignments, and has several national centers of competence. Oslo University Hospital is responsible for approximately 50 percent of all medical and health care research conducted at Norwegian hospitals, and is a significant role player within the education of a large variety of health care personnel.&nbsp; Do you want to know more about us? Read more here:&nbsp;<a href="https://www.oslo-universitetssykehus.no/om-oss/jobb-og-utdanning/arbeidsplassen-var" rel="nofollow">https://www.oslo-universitetssykehus.no/om-oss/jobb-og-utdanning/arbeidsplassen-var</a><h4 class="navds-heading navds-heading--xsmall navds-typo--spacing">Kontaktinformasjon</h4>Runar Almaas,&nbsp;Avdelingsleder,&nbsp;+4741321932 
<h4 class="navds-heading navds-heading--xsmall navds-typo--spacing">Arbeidssted</h4>Sognsvannsveien 20 
0372&nbsp;Oslo 
<h4 class="navds-heading navds-heading--xsmall navds-typo--spacing">Nøkkelinformasjon:</h4>Arbeidsgiver: Oslo universitetssykehus HF 
 
Referansenr.: 4987715611 
Stillingsprosent: 100% 
Contract 
Startdato: 01.09.2025 
Sluttdato: 31.08.2028 
Søknadsfrist: 10.07.2025